I don't need to do it often, but when I do this is where I start
This is super helpful when your running low on space and you need to quickly find the offenders.
Top 20 Files Directories
cd / && sudo du -ahx . | sort -rh | head -20
6.1G .
3.7G ./usr
2.2G ./usr/src
1.2G ./home/ubuntu
1.2G ./home
924M ./usr/lib
861M ./home/ubuntu/trading
740M ./var
540M ./var/lib
379M ./home/ubuntu/trading/oanda_fx
373M ./home/ubuntu/trading/oanda_fx/logs
308M ./lib
302M ./var/lib/snapd
270M ./usr/lib/x86_64-linux-gnu
259M ./usr/share
259M ./lib/modules
240M ./usr/lib/chromium-browser
218M ./home/ubuntu/.local/lib/python3.6/site-packages
218M ./home/ubuntu/.local/lib/python3.6
218M ./home/ubuntu/.local/lib
sudo journalctl --vacuum-size=50M